GRK2 Polyclonal Antibody

• Background:

  The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.

• Abbreviation:

  ADRBK1

• UniProt:

  P25098

• Host:

  Rabbit

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Synthetic peptide of human ADRBK1

• Target:

  ADRBK1; Adrenergic beta receptor kinase 1; ARBK1; BARK; BARK1; Beta adrenergic receptor kinase 1; Beta ARK 1; Beta ARK1; Beta-adrenergic receptor kinase 1; Beta-ARK-1; FLJ16718; G protein coupled receptor kinase 2; G-protein coupled receptor kinase 2; GRK2

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  IHC

• Field of Research:

  Cancer; Neuroscience; Signal Transduction

• Purification:

  Affinity purification

• Concentration:

  0.5 mg/mL

• Dilution:

  IHC 1:100-1:300

• Buffer:

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Citation 01:

  https://www.sciencedirect.com/science/article/pii/S0753332221011975

• Isotype:

  IgG