DNM1 Polyclonal Antibody

• Background:

  This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described.

• Abbreviation:

  DNM1

• UniProt:

  Q05193

• Host:

  Rabbit

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Synthetic peptide of human DNM1

• Target:

  B dynamin; D100; DNM 1; DNM; DNM1; DYN1; Dynamin; Dynamin-1; Dynamin1

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB

• Field of Research:

  Cancer; Neuroscience; Signal Transduction

• Purification:

  Affinity purification

• Concentration:

  0.4 mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  97kDa

• Isotype:

  IgG