BCL2 Polyclonal Antibody

CAT: 0763-E-AB-15522-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0763-E-AB-15522-01Size:20 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends.
Abbreviation
BCL2
UniProt
P10415
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic peptide of human BCL2
Target
Apoptosis regulator Bcl 2; Apoptosis regulator Bcl-2; Apoptosis regulator Bcl2; AW986256; B cell CLL/lymphoma 2; B cell leukemia/lymphoma 2; Bcl-2; Bcl2; BCL2; C430015F12Rik; D630044D05Rik; D830018M01Rik; Leukemia/lymphoma; B-cell;2; Oncogene B-cell leukemia 2; PPP1R50; Protein phosphatase 1; regulatory subunit 50
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Cancer; Cell Biology; Metabolism; Signal Transduction
Purification
Affinity purification
Concentration
0.6 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
22kDa
Citation 01
https://www.sciencedirect.com/science/article/pii/S1043661822003930
Citation 02
https://www.mdpi.com/1975256
Citation 03
https://www.mdpi.com/1574002
Citation 04
https://www.mdpi.com/1422-0067/22/15/8117
Citation 05
https://www.spandidos-publications.com/10.3892/ijmm.2019.4432
Citation 06
https://onlinelibrary.wiley.com/doi/abs/10.1002/mrd.23280
Citation 07
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773939/
Isotype
IgG

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