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CD236 Polyclonal Antibody

CAT: 0763-E-AB-15080-02Size: 60 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-15080-02Size:60 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants.
Abbreviation
GYPC
UniProt
P04921
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant protein of human GYPC
Target
CD236; CD236R; GE; GLPC; GLPC; Glycoconnectin; Glycophorin C (Gerbich blood group) ; Glycophorin D; Glycophorin-C; Glycophorin-D; Glycoprotein beta; GPC; GPD; Gypc; GYPD; MGC117309; MGC126191; MGC126192; PAS 2; PAS 2'; PAS-2''; Sialoglycoprotein D
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Cardiovascular
Purification
Affinity purification
Concentration
0.4 mg/mL
Dilution
IHC 1:100-1:300
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

UniProtKB · P04921

Glycophorin-C

GLPC_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P04921
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
GYPC
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B2R522, Q53SV9, Q92642
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Molecular function

Blood group antigen

Cellular component

Cell membraneMembrane

PTM

GlycoproteinPhosphoprotein

Ligand

Sialic acid

Domain

TransmembraneTransmembrane helix

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