ACTA1 Polyclonal Antibody

• Background:

  The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.

• Abbreviation:

  ACTA1

• UniProt:

  P68133

• Host:

  Rabbit

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Recombinant protein of human ACTA1

• Target:

  A actin; ACTA; ACTA1; Actin alpha skeletal muscle; Actin; actin; alpha 1; skeletal muscle 1; actin; alpha 1; skeletal muscle; Actin; alpha skeletal muscle; actina; actine; ACTS; aktin; Alpha Actin 1; Alpha skeletal muscle Actin; alpha skeletal muscle; alpha-actin; Alpha-actin-1; ASMA; CFTD; CFTD1; CFTDM; MPFD; NEM1; NEM2; NEM3; nemaline myopathy type 3

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB; IHC

• Field of Research:

  Cancer; Signal Transduction; Tags and Cell Markers

• Purification:

  Affinity purification

• Concentration:

  0.5 mg/mL

• Dilution:

  WB 1:500-1:2000; IHC 1:50-1:200

• Buffer:

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  42kDa

• Isotype:

  IgG