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E-Selectin Polyclonal Antibody

CAT: 0763-E-AB-14325-02Size: 60 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-14325-02Size:60 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis.
Abbreviation
SELE
UniProt
P16581
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant protein of human SELE
Target
CD26E; CD62 antigen-like family member E; CD62E; E selectin; E-selectin; ELAM; ELAM-1; ELAM1; Endothelial adhesion molecule 1; Endothelial leukocyte adhesion molecule 1; ESEL; LECAM2; Leukocyte-endothelial cell adhesion molecule 2; LYAM2; Sele; Selectin E
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Cardiovascular; Immunology; Stem Cells
Purification
Affinity purification
Concentration
0.3 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

UniProtKB · P16581

E-selectin

LYAM2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P16581
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SELE
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
A2RRD6, P16111
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Ligand

CalciumLectinMetal-binding

Biological process

Cell adhesion

Cellular component

Cell membraneMembrane

PTM

Disulfide bondGlycoprotein

Domain

EGF-like domainRepeatSignalSushiTransmembraneTransmembrane helix

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