CREB2 Polyclonal Antibody

CAT: 0763-E-AB-13942-02Size: 60 µLDry Ice: NoHazardous: No

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CAT#:0763-E-AB-13942-02Size:60 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2) . The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain.

Abbreviation

ATF4

UniProt

P18848

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant protein of human ATF4

Target

Activating transcription factor 4; ATF 4; ATF4; ATF4 protein; ATF4; cAMP-dependent transcription factor ATF-4; cAMP-responsive element-binding protein 2; CREB 2; CREB-2; CREB2; Cyclic AMP dependent transcription factor ATF 4; Cyclic AMP response element binding protein 2; Cyclic AMP-dependent transcription factor ATF-4; Cyclic AMP-responsive element-binding protein 2; DNA binding protein TAXREB67; DNA-binding protein TAXREB67; Tax Responsive Enhancer Element B67; Tax-responsive enhancer element-binding protein 67; TaxREB67; TXREB

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Cancer; Epigenetics and Nuclear Signaling

Purification

Affinity purification

Concentration

0.7 mg/mL

Dilution

IHC 1:50-1:200

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG

UniProtKB · P18848

Cyclic AMP-dependent transcription factor ATF-4

ATF4_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P18848
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: ATF4
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: cAMP-dependent transcription factor ATF-4
EC number: —
Processing: —
Secondary accessions: Q96AQ3, Q9UH31

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationHydroxylationIsopeptide bondPhosphoproteinUbl conjugation

Molecular function

ActivatorDNA-bindingRepressor

Biological process

Biological rhythmsTranscriptionTranscription regulation

Cellular component

Cell membraneCytoplasmCytoskeletonMembraneNucleus

Domain

Coiled coil

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Alternative Products

Catalog	Name
RD75085A-01	CREB2 Polyclonal Antibody
ANT-35604-100ug	Human ATF4/CREB2 Antibody
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MBS1569575-01	Anti-Human ATF4/CREB2 Antibody
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