TLR2 Polyclonal Antibody

• Background:

  The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.

• Abbreviation:

  TLR2

• UniProt:

  O60603

• Host:

  Rabbit

• Reactivity:

  Human; Mouse

• Immunogen:

  Recombinant protein of human TLR2

• Target:

  CD282; CD282 antigen; TIL 4; TIL4; TLR 2; TLR2; TLR2; Toll like receptor 2; Toll like receptor 2 precursor; Toll-like receptor 2; Toll/interleukin 1 receptor like 4; Toll/interleukin 1 receptor like protein 4; Toll/interleukin receptor like protein 4; Toll/interleukin-1 receptor-like protein 4

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  IHC

• Field of Research:

  Cancer; Cardiovascular; Immunology; Microbiology; Signal Transduction

• Purification:

  Affinity purification

• Concentration:

  0.3 mg/mL

• Dilution:

  IHC 1:25-1:100

• Buffer:

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Isotype:

  IgG