COL18A1 Polyclonal Antibody

CAT: 0763-E-AB-13213-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0763-E-AB-13213-01Size:20 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. The proteolytically produced C-terminal fragment of type XVIII collagen is endostatin, a potent antiangiogenic protein. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Abbreviation
COL18A1
UniProt
P39060
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Synthetic peptide of human COL18A1
Target
Antiangiogenic agent; COIA1; Col18a1; Collagen alpha 1 (XVIII) chain; Collagen type XVIII alpha 1; Endostatin; KNO; KNO1; KS; Multi functional protein MFP
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Cardiovascular; Signal Transduction
Purification
Affinity purification
Concentration
0.6 mg/mL
Dilution
IHC 1:100-1:300
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

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