ARIH2 Polyclonal Antibody

• Background:

  TRIAD1, also known as ARIH2 (ariadne homolog 2) or ARI2, is a 493 amino acid protein that contains one IBR-type zinc finger and two RING-type zinc fingers and belongs to the ariadne subfamily of RBR proteins. Localized to the nucleus, TRIAD1 interacts with UBE2L3 and is thought to act as an E3 ubiquitin-protein ligase, functioning to accept ubiquitin from E2 ubiquitin-conjugating enzymes and transfer the acquired ubiquitin residue to target substrates. TRIAD1 is subject to post-translational DNA damage-dependent phosphorylation, probably by ATM or ATR. The gene encoding TRIAD1 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci.

• Abbreviation:

  ARIH2

• UniProt:

  O95376

• Host:

  Rabbit

• Reactivity:

  Human; Mouse

• Immunogen:

  Synthetic peptide of human ARIH2

• Target:

  HT005; all trans retinoic acid inducible RING finger; Ari 2; Ari-2; ARI2; ARI2; Ariadne 2; Ariadne 2 protein homolog; ariadne homolog 2 (Drosophila) ; ariadne homolog 2; Ariadne RBR E3 ubiquitin protein ligase 2; ARIH 2; Arih2; E3 ubiquitin protein ligase ARIH2; E3 ubiquitin-protein ligase ARIH2; protein ariadne 2 homolog; Protein ariadne-2 homolog; Triad 1; TRIAD1; Triad1 protein; UIP48

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB

• Field of Research:

  Cell Biology; Epigenetics and Nuclear Signaling

• Purification:

  Affinity purification

• Concentration:

  0.6 mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  58kDa

• Isotype:

  IgG