ABCA4 Polyclonal Antibody

CAT: 0763-E-AB-12935-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0763-E-AB-12935-01Size:20 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White) . This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is a retina-specific ABC transporter with N-retinylidene-PE as a substrate. It is expressed exclusively in retina photoreceptor cells, indicating the gene product mediates transport of an essental molecule across the photoreceptor cell membrane. Mutations in this gene are found in patients diagnosed with Stargardt disease, a form of juvenile-onset macular degeneration. Mutations in this gene are also associated with retinitis pigmentosa-19, cone-rod dystrophy type 3, early-onset severe retinal dystrophy, fundus flavimaculatus, and macular degeneration age-related 2.
Abbreviation
ABCA4
UniProt
P78363
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic peptide of human ABCA4
Target
ABC 10; ABC A4; ABC transporter; retinal-specific; ABC10; ABCA 4; abcA4; ABCA4; ABCR; ARMD 2; ARMD2; ATP binding cassette 10; ATP binding cassette sub family A member 4; ATP binding cassette sub family A member4; ATP binding cassette transporter; ATP binding cassette transporter retinal specific; ATP binding cassette; sub family A (ABC1) ; member 4; ATP binding cassette; sub family A (ABC1) ; member4; ATP binding cassette10; ATP binding transporter; retina specific; ATP-binding cassette sub-family A member 4; CORD 3; CORD3; DKFZp781N1972; FFM; FLJ17534; Photoreceptor rim protein; Retina specific ABC transporter; Retinal specific ATP binding cassette transporter; Retinal-specific ATP-binding cassette transporter; RIM ABC transporter; RIM protein; RmP; RP 19; RP19; Stargardt disease protein; STGD; STGD1
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Neuroscience
Purification
Affinity purification
Concentration
0.2 mg/mL
Dilution
IHC 1:25-1:100
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

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