AKR1C1 Polyclonal Antibody

CAT: 0763-E-AB-12710-01Size: 20 µLDry Ice: NoHazardous: No

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CAT#:0763-E-AB-12710-01Size:20 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.

Abbreviation

AKR1C1

UniProt

Q04828

Host

Rabbit

Reactivity

Human

Immunogen

Synthetic peptide of human AKR1C1

Target

2-dihydrobenzene-1;2-diol dehydrogenase;20 alpha (3 alpha) hydroxysteroid dehydrogenase;20 ALPHA HSD;20 alpha hydroxysteroid dehydrogenase;20-alpha-HSD;20-alpha-hydroxysteroid dehydrogenase;20ALPHAHSD;2ALPHAHSD; AK1C1; AK1C1; AKR1C1; Aldo keto reductase family 1 member C1; aldo-keto reductase C; Aldo-keto reductase family 1 member C1; Aldo-keto reductase family;1 member 1; C9; Chlordecone reductase homolog; Chlordecone reductase homolog HAKRC; DD1; DD1/DD2; DDH; DDH1; Dihydrodiol dehydrogenase 1; Dihydrodiol dehydrogenase 1/2; dihydrodiol dehydrogenase 1;20-alpha (3-alpha) -hydroxysteroid dehydrogenase; dihydrodiol dehydrogenase isoform DD1; Dihydrodiol dehydrogenase; type 1; H37; HAKRC; HBAB; Hepatic dihydrodiol dehydrogenase; High affinity hepatic bile acid-binding protein; High-affinity hepatic bile acid-binding protein; Indanol dehydrogenase; MBAB; MGC8954; Trans-1; Trans-1;2 dihydrobenzene 1;2 diol dehydrogenase; Type II 3 alpha hydroxysteroid dehydrogenase

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Metabolism; Developmental Biology; Signal Transduction

Purification

Affinity purification

Concentration

0.2 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:50-1:200

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

37kDa

Isotype

IgG

UniProtKB · Q04828

Aldo-keto reductase family 1 member C1

AK1C1_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q04828
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: AKR1C1
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: 1.1.1.-, 1.1.1.112, 1.1.1.209, 1.1.1.210, 1.1.1.357, 1.1.1.51, 1.1.1.53, 1.1.1.62, 1.3.1.20
Processing: —
Secondary accessions: P52896, Q5SR15, Q7M4N2, Q9UCX2

Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Cellular component

Cytoplasm

Biological process

Lipid metabolism

Ligand

NADP

Molecular function

Oxidoreductase

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GTR18043906-01	AKR1C1 polyclonal antibody
GTR17878936	AKR1C1 Rabbit Polyclonal Antibody