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MMP26 Polyclonal Antibody

CAT: 0763-E-AB-12574-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-12574-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The encoded protein degrades type IV collagen, fibronectin, fibrinogen, casein, vitronectin, alpha 1-antitrypsin, alpha 2-macroglobulin, and insulin-like growth factor-binding protein 1, and activates MMP9 by cleavage. The protein differs from most MMP family members in that it lacks a conserved C-terminal protein domain.
Abbreviation
MMP26
UniProt
Q9NRE1
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic peptide of human MMP26
Target
Endometase; Matrilysin 2; Matrix Metalloproteinase 26; MMP 26
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Cancer; Cell Biology; Signal Transduction
Purification
Affinity purification
Concentration
0.4 mg/mL
Dilution
WB 1:200-1:1000
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
30kDa
Isotype
IgG

UniProtKB · Q9NRE1

Matrix metalloproteinase-26

MMP26_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9NRE1
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MMP26
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
MMP-26
EC number
3.4.24.-
Processing
Precursor
Secondary accessions
Q3MJ78, Q9GZS2, Q9NR87
Protein keywords

Ligand

CalciumMetal-bindingZinc

Biological process

Collagen degradation

Cellular component

Extracellular matrixSecreted

PTM

GlycoproteinZymogen

Molecular function

HydrolaseMetalloproteaseProtease

Technical term

Proteomics identificationReference proteome

Domain

Signal

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