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TNFRSF21 Polyclonal Antibody

CAT: 0763-E-AB-12371-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-12371-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB and MAPK8/JNK, and induce cell apoptosis. Through its death domain, this receptor interacts with TRADD protein, which is known to serve as an adaptor that mediates signal transduction of TNF-receptors. Knockout studies in mice suggested that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation.
Abbreviation
TNFRSF21
UniProt
O75509
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic peptide of human TNFRSF21
Target
TNFRSF 21; BM 018; BM018; CD358; Death receptor 6; DR 6; DR6; MGC31965; OTTHUMP00000039915; TNFR related death receptor 6; TNFRSF21; TNFRSF21 protein; TNR21; Tumor necrosis factor receptor superfamily member 21; Tumor necrosis factor receptor superfamily member 21 precursor
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Cell Biology
Purification
Affinity purification
Concentration
0.3 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
72kDa
Isotype
IgG

UniProtKB · O75509

Tumor necrosis factor receptor superfamily member 21

TNR21_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O75509
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
TNFRSF21
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
B2RDI9, Q0D2P5, Q96D86
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Biological process

Adaptive immunityApoptosisHost-virus interactionImmunity

Cellular component

Cell membraneMembrane

PTM

Disulfide bondGlycoproteinLipoproteinOxidationPalmitate

Molecular function

Receptor

Domain

RepeatSignalTransmembraneTransmembrane helix

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