DRD4 Polyclonal Antibody

• Background:

  This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats.

• Abbreviation:

  DRD4

• UniProt:

  P21917

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Synthetic peptide of human DRD4

• Target:

  D (2C) dopamine receptor; D (4) dopamine receptor (D (2C) dopamine receptor) .; D (4) dopamine receptor; D4 dopamine receptor; D4DR; Dopamine D4 receptor; DRD 4; Drd4; DRD4

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB; IHC

• Field of Research:

  Neuroscience

• Purification:

  Affinity purification

• Concentration:

  0.4 mg/mL

• Dilution:

  WB 1:500-1:2000; IHC 1:30-1:150

• Buffer:

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  48kDa

• Isotype:

  IgG