CK-14 Polyclonal Antibody

CAT: 0763-E-AB-12322-01Size: 20 µLDry Ice: NoHazardous: No

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CAT#:0763-E-AB-12322-01Size:20 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

This gene encodes a member of the keratin family, the most diverse group of intermediate filaments. This gene product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12-p11.

Abbreviation

KRT14

UniProt

P02533

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Synthetic peptide of human KRT14

Target

CK 14; CK-14; ck14; Cytokeratin 14; Cytokeratin-14; Cytokeratin14; Dowling Meara; EBS3; EBS4; Epidermolysis bullosa simplex; K14; K1C14; Keratin 14 (epidermolysis bullosa simplex; Dowling-Meara; Koebner) ; Keratin 14; Keratin; Keratin type I cytoskeletal 14; Keratin; type I cytoskeletal 14; Keratin-14; Keratin14; Koebner; Krt 14; Krt14; NFJ; OTTHUMP00000164624; type I cytoskeletal 14

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

Field of Research

Cancer; Signal Transduction

Purification

Affinity purification

Concentration

0.4 mg/mL

Dilution

WB 1:1000-1:5000

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

52kDa

Isotype

IgG

UniProtKB · P02533

Keratin, type I cytoskeletal 14

K1C14_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P02533
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: KRT14
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: —
Processing: —
Secondary accessions: Q14715, Q53XY3, Q9BUE3, Q9UBN2, Q9UBN3, Q9UCY4

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Domain

Coiled coil

Cellular component

CytoplasmIntermediate filamentKeratinNucleus

Disease

Disease variantEctodermal dysplasiaEpidermolysis bullosaPalmoplantar keratoderma

PTM

Disulfide bondPhosphoproteinUbl conjugation

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