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RHOB Polyclonal Antibody

CAT: 0763-E-AB-12248-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-12248-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Ras homolog gene family, member B, also known as RHOB, is a protein which in humans is encoded by the RHOB gene.RHOB is a member of the Rho GTP-binding protein family.Mediates apoptosis in neoplastically transformed cells after DNA damage. It is not necessary for development but affects cell adhesion and growth factor signaling in transformed cells. It plays a negative role in tumorigenesis as deletion causes tumor formation. It involved in intracellular protein trafficking of a number of proteins, and serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Required for genotoxic stress-induced cell death in breast cancer cells.
Abbreviation
RHOB
UniProt
P62745
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Synthetic peptide of human RHOB
Target
Aplysia RAS-related homolog 6; ARH6; ARHB; H6; MST081; MSTP081; oncogene RHO H6; ras homolog family member B; ras homolog gene family; member B; Rho cDNA clone 6; Rho related GTP binding protein RhoB Precursor; Rho-related GTP-binding protein RhoB; Rhob; RHOB; RHOH6
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Signal Transduction
Purification
Affinity purification
Concentration
0.4 mg/mL
Dilution
WB 1:1000-1:2000
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
22kDa
Isotype
IgG

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