RGS1 Polyclonal Antibody

CAT: 0763-E-AB-11534-01Size: 20 µLDry Ice: NoHazardous: No

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CAT#:0763-E-AB-11534-01Size:20 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

This gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.

Abbreviation

RGS1

UniProt

Q08116

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Recombinant protein of human RGS1

Target

1R20; B cell activation protein BL34; B-cell activation protein BL34; BL34; Early response protein 1R20; IER 1; IER1; Immediate early response 1 B cell specific; immediate-early response 1; B-cell specific; IR20; Regulator of G protein signalling 1; Regulator of G-protein signaling 1; RGS 1; RGS1; RGS1

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

Field of Research

Signal Transduction

Purification

Affinity purification

Concentration

0.3 mg/mL

Dilution

WB 1:500-1:2000

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

24kDa

Citation 01

https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-022-03526-0

Isotype

IgG

UniProtKB · Q08116

Regulator of G protein signaling 1

RGS1_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q08116
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: RGS1
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: RGS1
EC number: —
Processing: —
Secondary accessions: B2RDM9, B4DZY0, Q07918, Q9H1W2

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneCytoplasmMembrane

Molecular function

GTPase activationSignal transduction inhibitor

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Alternative Products

Catalog	Name
JOT-AP07798-01	RGS1 Polyclonal Antibody