HSD17B2 Polyclonal Antibody

• Background:

  17β-HSD2 (17β hydroxysteroid dehydrogenase type 2) belongs to the 17β-HSD family of proteins that regulate the availability of steroids within a tissue. 17β-HSD2 converts active steroids to their inactive form through its oxidative activity. It is a key player in the inactivation of Estradiol and testosterone. Due to the affects that 17β-HSD2 has on the availability of estrogen, it has been extensively investigated for playing a possible role in breast tumor development, colon cancer development and the pathophysiology of endometriosis.

• Abbreviation:

  HSD17B2

• UniProt:

  P37059

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Recombinant protein of human HSD17B2

• Target:

  17 beta HSD 2;17-beta-HSD 2;17-beta-hydroxysteroid dehydrogenase type 2;20 alpha HSD;20 alpha hydroxysteroid dehydrogenase;20 alpha-hydroxysteroid dehydrogenase;20-alpha-HSD; DHB2; E2DH; EDH17B2; Estradiol 17-beta-dehydrogenase 2; HSD17; Hsd17b2; Hydroxysteroid (17 beta) dehydrogenase 2; Microsomal 17 beta hydroxysteroid dehydrogenase; Microsomal 17-beta-hydroxysteroid dehydrogenase; SDR9C2; Short chain dehydrogenase/reductase family 9C; member 2; Testosterone 17 beta dehydrogenase; Testosterone 17-beta-dehydrogenase

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB; IHC

• Field of Research:

  Cancer; Signal Transduction

• Purification:

  Affinity purification

• Concentration:

  0.5 mg/mL

• Dilution:

  WB 1:500-1:2000; IHC 1:50-1:200

• Buffer:

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  43kDa

• Isotype:

  IgG