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FANCG Polyclonal Antibody

CAT: 0763-E-AB-11217-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-11217-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2) . The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group G.
Abbreviation
FANCG
UniProt
O15287
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant protein of human FANCG
Target
DNA repair protein XRCC9; FAG; FANCG; FANCG; Fanconi anaemia complementation group G; Fanconi anemia group G protein; Protein FACG; X ray repair; complementing defective; in Chinese hamster cells 9; X-ray repair; complementing defective; in Chinese hamster;9; XRCC9
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Epigenetics and Nuclear Signaling
Purification
Affinity purification
Concentration
1 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

UniProtKB · O15287

Fanconi anemia group G protein

FANCG_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O15287
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
FANCG
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
Protein FACG
EC number
—
Processing
—
Secondary accessions
—
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Cellular component

CytoplasmNucleus

Disease

Disease variantFanconi anemia

Biological process

DNA damageDNA repair

PTM

Phosphoprotein

Domain

RepeatTPR repeat

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