ATXN1 Polyclonal Antibody

CAT: 0763-E-AB-10990-01Size: 20 µLDry Ice: NoHazardous: No

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CAT#:0763-E-AB-10990-01Size:20 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes. ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5), are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions.

Abbreviation

ATXN1

UniProt

P54253

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant protein of human ATXN1

Target

Alternative ataxin1; Ataxin-1; ATX1; ATX1; Atxn1; D6S504E; OTTHUMP00000016065; SCA1; Spinocerebellar ataxia type 1 protein

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Epigenetics and Nuclear Signaling; Neuroscience

Purification

Affinity purification

Concentration

0.4 mg/mL

Dilution

IHC 1:50-1:200

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG

UniProtKB · P54253

Ataxin-1

ATX1_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P54253
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: ATXN1
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: —
Processing: —
Secondary accessions: Q17S02, Q9UJG2, Q9Y4J1

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicingTriplet repeat expansion

Cellular component

CytoplasmNucleus

Molecular function

DNA-bindingRepressorRNA-binding

PTM

Isopeptide bondPhosphoproteinUbl conjugation

Disease

NeurodegenerationSpinocerebellar ataxia

Biological process

TranscriptionTranscription regulation

Related Products

Catalog	Name
E-EL-H0519-01	Human ATXN1-Ataxin 1- ELISA Kit
E-CL-R0061-01	Rat ATXN1 -Ataxin 1- CLIA Kit
E-EL-M0162	ELISA kit for Mouse ATXN1 (Ataxin 1)
E-CL-H0422-01	Human ATXN1 -Ataxin 1- CLIA Kit
E-EL-R0080	ELISA kit for Rat ATXN1 (Ataxin 1)
E-CL-M0122-01	Mouse ATXN1 -Ataxin 1- CLIA Kit
E-AB-18525-01	ATXN3 Polyclonal Antibody
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E-AB-52456-01	ATXN3 Polyclonal Antibody
E-AB-53584-01	ATXN7 Polyclonal Antibody

Alternative Products

Catalog	Name
MBS2527447-01	ATXN1 Polyclonal Antibody
E10G13868	ATXN1 Rabbit Polyclonal Antibody
P08058-01	Rabbit Polyclonal Antibody to ATXN1
TRV-011023-01	Polyclonal Antibody to Ataxin 1 (ATXN1)
CAU27779-01	Ataxin 1 (ATXN1) Polyclonal Antibody
APG03176G	Polyclonal ATXN1 Antibody (internal region)
GTR18211081	ATXN1 (C) Antibody, Rabbit Polyclonal
TA332986	Ataxin 1 (ATXN1) Rabbit Polyclonal Antibody
TRV-045324-01	Anti-Ataxin 1 (ATXN1) Polyclonal Antibody
10R-11203	ATXN1 antibody