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EPHB6 Polyclonal Antibody

CAT: 0763-E-AB-10907-02Size: 60 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-10907-02Size:60 µL
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Background
This gene encodes a member of a family of transmembrane proteins that function as receptors for ephrin-B family proteins. Unlike other members of this family, the encoded protein does not contain a functional kinase domain. Activity of this protein can influence cell adhesion and migration. Expression of this gene is downregulated during tumor progression, suggesting that the protein may suppress tumor invasion and metastasis. Alternative splicing results in multiple transcript variants.
Abbreviation
EPHB6
UniProt
O15197
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant protein of human EPHB6
Target
EPH receptor B6; Ephb6; EPHB6; Ephrin type B receptor 6 precursor; Ephrin type-B receptor 6; HEP; MGC129910; MGC129911; Tyrosine protein kinase defective receptor EPH 6; Tyrosine-protein kinase-defective receptor EPH-6
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Neuroscience
Purification
Affinity purification
Concentration
0.4 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

UniProtKB · O15197

Ephrin type-B receptor 6

EPHB6_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O15197
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
EPHB6
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
A4D2I7, A8CDT5, D3DXD3, Q2TB23, Q2TB24
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingNucleotide-binding

Cellular component

Cell membraneMembraneSecreted

PTM

GlycoproteinPhosphoprotein

Molecular function

Receptor

Domain

RepeatSignalTransmembraneTransmembrane helix