USP2 Polyclonal Antibody

CAT: 0763-E-AB-10878-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0763-E-AB-10878-01Size:20 µL
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Background
This gene encodes a member of the family of de-ubiquitinating enzymes, which belongs to the peptidase C19 superfamily. The encoded protein is a ubiquitin-specific protease which is required for TNF-alpha (tumor necrosis factor alpha) -induced NF-kB (nuclear factor kB) signaling. This protein deubiquitinates polyubiquitinated target proteins such as fatty acid synthase, murine double minute 2 (MDM2), MDM4/MDMX and cyclin D1. MDM2 and MDM4 are negative regulators of the p53 tumor suppressor and cyclin D1 is required for cell cycle G1/S transition. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Abbreviation
USP2
UniProt
O75604
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant protein of human USP2
Target
41 kDa ubiquitin specific protease;41 kDa ubiquitin-specific protease; Deubiquitinating enzyme 2; Ubiquitin carboxyl terminal hydrolase 2; Ubiquitin carboxyl-terminal hydrolase 2; ubiquitin specific peptidase 2; Ubiquitin specific processing protease 2; Ubiquitin specific protease 12; Ubiquitin specific protease 9; Ubiquitin specific protease;41kD; Ubiquitin thioesterase 2; Ubiquitin thiolesterase 2; Ubiquitin-specific-processing protease 2; Ubiquitin-specific-processing protease testis; UBP-t; UBP2; UBP41; USP2; USP9
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cell Biology; Epigenetics and Nuclear Signaling
Purification
Affinity purification
Concentration
0.3 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

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