Products for Research Use Only

IL18R1 Polyclonal Antibody

CAT: 0763-E-AB-10105-01Size: 20 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0763-E-AB-10105-01Size:20 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Abbreviation
IL18R1
UniProt
Q13478
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant protein of human IL18R1
Target
CD218 antigen-like family member A; CD218a; CDw218a; CDw218a antigen; IL 1Rrp; IL-18R-1; IL-18R1; IL-1Rrp; IL1 receptor related protein; IL1 receptor-related protein; IL18R; IL18R1; IL18RA; Il18ralpha; IL1R-rp; IL1RRP; Interleukin 18 receptor 1; Interleukin 18 receptor; alpha chain; Interleukin-18 receptor 1
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Immunology
Purification
Affinity purification
Concentration
0.6 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

UniProtKB · Q13478

Interleukin-18 receptor 1

IL18R_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q13478
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
IL18R1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
IL-18R-1, IL-18R1
EC number
3.2.2.6
Processing
Precursor
Secondary accessions
B2R9Y5, Q52LC9
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

Disulfide bondGlycoprotein

Molecular function

HydrolaseReceptor

Domain

Immunoglobulin domainRepeatSignalTransmembraneTransmembrane helix

Biological process

Inflammatory response

Cellular component

Membrane

Ligand

NAD