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IL13RA1 Polyclonal Antibody

CAT: 0763-E-AB-10102-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-10102-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.
Abbreviation
IL13RA1
UniProt
P78552
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Recombinant protein of human IL13RA1
Target
BB128O4.2.1 (interleukin 13 receptor; alpha 1) ; Cancer/testis antigen 19; CD213a1; CD213A1 Antigen; CT 19; CT19; I13R1; IL 13 receptor subunit alpha 1; IL 13R alpha 1; IL 13R subunit alpha 1; IL 13Ra; IL 13RA1; IL-13 receptor subunit alpha-1; IL-13R subunit alpha-1; IL-13R-alpha-1; IL-13RA1; IL13 receptor alpha 1 chain; IL13R; IL13RA; Il13ra1; Interleukin 13 receptor alpha 1; Interleukin 13 receptor alpha 1 chain; interleukin 13 receptor subunit alpha 1; Interleukin-13 receptor subunit alpha-1; NR 4; NR4
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Immunology; Signal Transduction
Purification
Affinity purification
Concentration
0.9 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

UniProtKB · P78552

Interleukin-13 receptor subunit alpha-1

I13R1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P78552
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
IL13RA1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
IL-13 receptor subunit alpha-1, IL-13R subunit alpha-1, IL-13R-alpha-1, IL-13RA1
EC number
—
Processing
Precursor
Secondary accessions
O95646, Q5JSL4, Q99656, Q9UDY5
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

PTM

Disulfide bondGlycoprotein

Cellular component

Membrane

Molecular function

Receptor

Domain

RepeatSignalTransmembraneTransmembrane helix