PE Anti-Human CD80 Antibody[2D10]

• Background:

  CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

• Abbreviation:

  CD80

• Gene ID:

  941

• UniProt:

  P33681

• Host:

  Mouse

• Reactivity:

  Human

• Target:

  B7BB1; B7-1; T-lymphocyte activation antigen CD80

• Clonality:

  Monoclonal

• Clone:

  2D10

• Conjugation:

  PE

• Applications:

  FCM

• Field of Research:

  Immunology; Innate Immunity

• Concentration:

  5 μL/Test

• Buffer:

  Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

• Citation 01:

  https://www.sciencedirect.com/science/article/pii/S1756464625001239

• Citation 02:

  https://www.hindawi.com/journals/bmri/2022/3946754/

• Citation 03:

  https://link.springer.com/article/10.1007/s11033-025-10517-z

• Recommended Usage:

  The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

• Isotype:

  Mouse IgG1, κ