Elab Fluor® Red 780 Anti-Rat CD45 Antibody[OX-1]

• Background:

  CD45 is a 180-220 kD protein also known as leukocyte common antigen (LCA) . It is a protein tyrosine phosphatase with multiple isoforms differing as a result of alternative splicing of the extracellular domain and glycosylation. CD45 is expressed on all hematopoietic cells except erythrocytes and platelets; isoform expression depends on cell type, activation state, and cell maturation. CD45 functions in signal transduction through T and B cell antigen receptors. CD45 has been shown to interact with various proteins including galectin-1, CD2, CD3, and CD4. The OX-1 antibody has been shown to partially inhibit NK cell-mediated lysis of syngeneic tumor cells in vitro.

• Abbreviation:

  CD45

• Gene ID:

  19265

• UniProt:

  P04157

• Host:

  Mouse

• Reactivity:

  Rat

• Target:

  LCALy-5T200; Leukocyte common antigen; Ptprc; Receptor-type tyrosine-protein phosphatase C

• Clonality:

  Monoclonal

• Clone:

  OX-1

• Conjugation:

  Elab Fluor®Red 780

• Applications:

  FCM

• Field of Research:

  Cell Biology; Immunology; Inhibitory Molecules; Neuroscience; Neuroscience Cell Markers

• Concentration:

  0.5 mg/mL

• Buffer:

  Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

• Recommended Usage:

  6

• Isotype:

  Mouse IgG1, κ