APC Anti-Human CD11b Antibody[ICRF44]

• Background:

  CD11b is a 165-170 kD type I transmembrane glycoprotein also known as αMintegrin, Mac-1, CR3, and C3biR. CD11b non-covalently associates with integrin β2 (CD18) and is expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b/CD18 is critical for the transendothelial migration of monocytes and neutrophils. It is also involved in granulocyte adhesion, phagocytosis, and neutrophil activation. CD11b/CD18 interacts with ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4, CD14, CD23, heparin, iC3b, fibrinogen, and factor X.

• Abbreviation:

  CD11b

• Gene ID:

  3684

• UniProt:

  P11215

• Host:

  Mouse

• Reactivity:

  Human

• Target:

  CD11 antigen-like family member B; CD11b; CR-3 alpha chain; Integrin alpha-M; Itgam; Leukocyte adhesion receptor MO1

• Clonality:

  Monoclonal

• Clone:

  ICRF44

• Conjugation:

  APC

• Applications:

  FCM

• Field of Research:

  Cell Adhesion; Cell Biology; Costimulatory Molecules; Immunology; Innate Immunity; Neuroscience; Neuroscience Cell Markers

• Concentration:

  5 μL/Test

• Buffer:

  Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

• Citation 01:

  https://europepmc.org/article/pmc/pmc10897903?javascript_support=no

• Recommended Usage:

  The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

• Isotype:

  Mouse IgG1, κ