DBCO-mPEG (MW 5kDa)
CAT:
804-HY-140319-03
Size:
25 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
DBCO-mPEG (MW 5kDa)
- UNSPSC Description: DBCO-mPEG (MW 5kDa) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-mPEG (MW 5kDa) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
- Target Antigen: PROTAC Linkers
- Type: Reference compound
- Related Pathways: PROTAC
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/dbco-mpeg-mw-5kda.html
- Solubility: Chloroform : 125 mg/mL (ultrasonic;warming)
- Smiles: O=C(CCC(NCCOCCOC)=O)N1CC2=CC=CC=C2C#CC3=C1C=CC=C3.[n].[MW 5kDa]
- Molecular Weight: 5000(Average)
- References & Citations: [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
- Shipping Conditions: Blue Ice
- Clinical Information: No Development Reported