PerCP/Cyanine5.5 Anti-Mouse CD49b/pan-NK cells Antibody[DX5]

• Background:

  DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin α chain also known as α2 integrin, VLA-2 α chain, and integrin α2 chain. CD49b non-covalently associates with CD29 (β1 integrin) to form the CD49b/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8+ T cells (this population can be significantly increased following viral infection) . DX5 is used for the identification and isolation of NK cells, and is especially useful for identifying NK cells in mice lacking the NK1.1 antigen.

• Abbreviation:

  CD49b

• Gene ID:

  16398

• UniProt:

  Q62469

• Host:

  Rat

• Reactivity:

  Mouse

• Target:

  CD49 antigen-like family member B; CD49b; Collagen receptor; GPIa; Integrin alpha-2; Platelet membrane glycoprotein Ia; VLA-2 subunit alpha; pan-NK cells

• Clonality:

  Monoclonal

• Clone:

  DX5

• Conjugation:

  PerCP/Cyanine 5.5

• Applications:

  FCM

• Field of Research:

  Cell Adhesion; Cell Biology; Immunology; Innate Immunity

• Concentration:

  5 μL/Test

• Buffer:

  Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

• Recommended Usage:

  The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

• Isotype:

  Rat IgM, κ