APC Anti-Mouse CD3 Antibody[17A2]

• Background:

  CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.

• Abbreviation:

  CD3

• Gene ID:

  12500;12501;12502;12503

• UniProt:

  P04235; P11942; P22646; P24161

• Host:

  Rat

• Reactivity:

  Mouse

• Target:

  CD3; CD3E/D/G/Z; CD3e/d/g/z; T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain

• Clonality:

  Monoclonal

• Clone:

  17A2

• Conjugation:

  APC

• Applications:

  FCM

• Field of Research:

  Immunology

• Concentration:

  5 μL/Test

• Buffer:

  Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

• Citation 01:

  https://pubs.acs.org/doi/abs/10.1021/acsnano.4c11412

• Citation 02:

  https://pubs.acs.org/doi/abs/10.1021/acsnano.4c16788

• Citation 03:

  https://www.nature.com/articles/s41467-025-60448-3

• Citation 04:

  https://www.sciencedirect.com/science/article/pii/S0142961223001552

• Citation 05:

  https://www.sciencedirect.com/science/article/pii/S1359836823004031

• Citation 06:

  https://www.sciencedirect.com/science/article/pii/S0142961225000158

• Citation 07:

  https://www.sciencedirect.com/science/article/pii/S0142961224000085

• Citation 08:

  https://academic.oup.com/cardiovascres/advance-article/doi/10.1093/cvr/cvae079/7655666

• Citation 09:

  https://www.sciencedirect.com/science/article/pii/S0168365923005461

• Recommended Usage:

  The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

• Isotype:

  Rat IgG2b, κ