AF/LE Purified Anti-Mouse CD3 Antibody[17A2]

• Background:

  CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.

• Abbreviation:

  CD3

• Gene ID:

  12500;12501;12502;12503

• UniProt:

  P04235; P11942; P22646; P24161

• Host:

  Rat

• Reactivity:

  Mouse

• Immunogen:

  Recombinant Mouse CD3 protein

• Target:

  CD3; CD3E/D/G/Z; CD3e/d/g/z; T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain

• Clonality:

  Monoclonal

• Clone:

  17A2

• Conjugation:

  None (AF/LE)

• Applications:

  FCM

• Field of Research:

  Immunology

• Purification:

  >98%, Protein A/G purified

• Concentration:

  ≥ 1 mg/mL

• Dilution:

  66

• Buffer:

  Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

• Recommended Usage:

  6

• Isotype:

  Rat IgG2b, κ