Purified Anti-Mouse MHC II (I-A/I-E) Antibody[M5/114]

• Background:

  These class II molecules are expressed on antigen presenting cells (including B cells) and a subset of T cells from H-2b, d, q, r bearing mice and are involved in antigen presentation to T cells expressing CD3/TCR and CD4 proteins.

• Abbreviation:

  MHC II (I-A/I-E)

• UniProt:

  P14483; O78196

• Host:

  Rat

• Reactivity:

  Mouse

• Immunogen:

  Recombinant Mouse MHC class II protein

• Target:

  H2-Ab1/Eb1; I-E beta MHC class II; MHC class II; MHC class II H2-IA-beta-psi; Major histocompatibility protein class II beta chain

• Clonality:

  Monoclonal

• Clone:

  M5/114

• Conjugation:

  Unconjugated

• Applications:

  FCM

• Field of Research:

  Immunology; Innate Immunity

• Purification:

  >98%, Protein A/G purified

• Concentration:

  ≥ 1 mg/mL

• Dilution:

  66

• Buffer:

  Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

• Citation 01:

  https://www.sciencedirect.com/science/article/pii/S2211383525002382

• Recommended Usage:

  6

• Isotype:

  Rat IgG2b, κ