Purified Mouse IgG2a, κ Isotype Control[C1.18.4]

• Background:

  NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.

• Host:

  Mouse

• Clonality:

  Monoclonal

• Clone:

  C1.18.4

• Conjugation:

  Unconjugated

• Applications:

  FCM

• Concentration:

  ≥ 1 mg/mL

• Buffer:

  Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

• Recommended Usage:

  Each lot of this antibody is quality control tested by flow cytometric analysis as negative control. Use at concentrations comparable to those of the specific antibody of interest.

• Isotype:

  Mouse IgG2a, κ