cIAP1 Ligand-Linker Conjugates 5

• Product Name Alternative:

  E3 ligase Ligand-Linker Conjugates 39

• UNSPSC Description:

  cIAP1 Ligand-Linker Conjugates 5 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 5 can be used to design SNIPERs[1].

• Target Antigen:

  E3 Ligase Ligand-Linker Conjugates

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/e3-ligase-ligand-linker-conjugates-39.html

• Solubility:

  10 mM in DMSO

• Smiles:

  C[C@H](N(C(OC(C)(C)C)=O)C)C(N[C@@H](C1CCCCC1)C(N(CCC2)[C@@H]2C3=NC(C(C4=CC=CC(OCCOCCOCCN)=C4)=O)=CS3)=O)=O

• Molecular Weight:

  729.93

• References & Citations:

  [1]Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2113688-20-1