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Zelminemab

CAT: 0804-HY-P99509-01Size: 1 mgDry Ice: YesHazardous: No
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CAT#:0804-HY-P99509-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Zelminemab (AMG-301) is a humanized monoclonal antibody that inhibits PACAP type I (PAC1) receptor[1].
CAS Number
2225850-33-7
Product Name Alternative
AMG-301
UNSPSC
12352203
Target
Adenylate Cyclase
Type
Inhibitory Antibodies
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/zelminemab.html
Purity
99.0
Solubility
10 mM in DMSO
Smiles
[Zelminemab]
Molecular Weight
(145.22 kDa)
References & Citations
[1]Eloisa Rubio-Beltrán, et al. PACAP38 and PAC1 receptor blockade: a new target for headache? J Headache Pain. 2018 Aug 7;19 (1) :64. |[2]Hoffmann J, et al. PAC-1 receptor antibody modulates nociceptive trigeminal activity in rat. Cephalalgia. 2016;36 (1S) :141–141.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 2

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