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DNA PKcs Rabbit Polyclonal Antibody

CAT: 0013-GTR17765694-01Size: 50 μLDry Ice: NoHazardous: No
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CAT#:0013-GTR17765694-01Size:50 μL
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Description
DNA PKcs Rabbit Polyclonal Antibody
Product Name Alternative
DNA-PKC; DNA-PKcs; DNAPK; DNAPKc; DNPK1; HYRC; HYRC1; IMD26; S473K; XRCC7; p350; DNAPDcs; DOXNPH; dxnph; p460; scid; slip; PRKDC_HUMAN; PRKDC; DNA-PK catalytic subunit; Ser-473 kinase (S473K) ; 2.7.11.1; PRKDC_MOUSE; protein kinase, DNA-activated, catalytic subunit; protein kinase, DNA-activated, catalytic polypeptide; DNA-dependent protein kinase catalytic subunit
UniProt
P78527
Reactivity
Human, Rat
Immunogen
KLH conjugated synthetic peptide derived from human DNA PKcs (151-300/4128aa)
Target
PRKDC
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
DNA / RNA, DNA Repair, DNA and RNA, Epigenetics and Nuclear Signaling
Purification
Affinity purified by Protein A
Concentration
1mg/ml
Dilution
IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500
Form
Liquid
Molecular Weight
454 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Prediction Reactivity
Bovine, Canine, Equine, Gallus, Mouse, Rabbit
Tested Applications
IF, IHC-Fr, IHC-P
Host or Source
Rabbit
Preservative
0.01M TBS (pH7.4) with 1% rAlbumin, 0.02% Proclin300 and 50% Glycerol.
Isotype
IgG

UniProtKB · P78527

DNA-dependent protein kinase catalytic subunit

PRKDC_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P78527
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PRKDC
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
DNA-PK catalytic subunit, DNA-PKcs
EC number
2.7.11.1
Processing
—
Secondary accessions
P78528, Q13327, Q13337, Q14175, Q59H99, Q7Z611, Q96SE6, Q9UME3
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingNucleotide-binding

Biological process

Biological rhythmsDNA damageDNA recombinationDNA repairImmunityInnate immunityRibosome biogenesis

Cellular component

CytoplasmNucleus

Disease

Disease variantSCID

Molecular function

DNA-bindingKinaseSerine/threonine-protein kinaseTransferase

Domain

RepeatTPR repeat

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