Trihexosylceramide (d18:1/12:0)

Trihexosylceramide (d18:1/12:0)

• CAS Number: 474943-80-1
• UNSPSC Description: Trihexosylceramide (d18:1/12:0) is a type of Trihexosylceramide. In the renal tissue of heterozygous Fabry's disease, the cytoplasm of glomerular epithelial cells appears foamy. Trihexosylceramide accumulated in glomerular epithelial cells as identified by immunostaining[1][2].
• Target Antigen: Others
• Type: Natural Products
• Related Pathways: Others
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/trihexosylceramide-d18-1-12-0.html
• Purity: 99.28
• Solubility: THF : 0.2 mg/mL (ultrasonic)
• Smiles: CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](NC(CCCCCCCCCCC)=O)CO[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)[C@H](O2)CO)[C@H](O1)CO
• Molecular Weight: 806.08
• References & Citations: [1]Wang JR, et al. Improved sphingolipidomic approach based on ultra-high performance liquid chromatography and multiple mass spectrometries with application to cellular neurotoxicity. Anal Chem. 2014 Jun 17;86(12):5688-96. |[2]Fukushima M, et al. A female heterozygous patient with Fabry's disease with renal accumulation of trihexosylceramide detected with a monoclonal antibody. Am J Kidney Dis. 1995 Dec;26(6):952-5.
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C (Powder, protect from light)
• Clinical Information: No Development Reported