Products for Research Use Only
RegisterLogin

Vistusertib

CAT: 0804-HY-15247-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-15247-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Vistusertib (AZD2014) is an ATP competitive mTOR inhibitor with an IC50 of 2.81 nM. AZD2014 inhibits both mTORC1 and mTORC2 complexes.
CAS Number
1009298-59-2
Product Name Alternative
AZD2014
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Autophagy; mTOR
Type
Reference compound
Related Pathways
Apoptosis; Autophagy; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/AZD2014.html
Purity
99.6900
Solubility
DMSO : ≥ 50 mg/mL
Smiles
O=C(NC)C1=CC=CC(C2=CC=C3C(N=C(N4[C@@H](C)COCC4)N=C3N5[C@@H](C)COCC5)=N2)=C1
Molecular Formula
C25H30N6O3
Molecular Weight
462.54
Precautions
H302, H315, H319, H335
References & Citations
[1]Guichard SM, et al. AZD2014, an inhibitor of mTORC1 and mTORC2, is highly effective in ER+ breast cancer when administered using intermittent or continuous schedules. Mol Cancer Ther. 2015 Nov;14 (11) :2508-18.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
MTOR; mTORC1; mTORC2

Alternative Products

CatalogName
T1961-01Vistusertib
MBS384294-01AZD2014 (Vistusertib)
C08855-5mgVistusertib (AZD2014)
A11303-100AZD2014 (Vistusertib) 100mg
204520Vistusertib (AZD-2014)
A11303-2AZD2014 (Vistusertib) 2mg

Popular Products