Pirlindole

• Description:

  Pirlindole is a selective and reversible MAO-A inhibitor[1]. Pirlindole is also an inhibitor of enterovirus-D68 and coxsackievirus B3 (CV-B3) [2].

• UNSPSC:

  12352005

• Target:

  Enterovirus; Monoamine Oxidase

• Type:

  Reference compound

• Related Pathways:

  Anti-infection; Neuronal Signaling

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/pirlindole.html

• Purity:

  98.90

• Solubility:

  10 mM in DMSO|DMSO : ≥ 5mg/mL

• Smiles:

  CC1=CC2=C(C=C1)N3C4=C2CCCC4NCC3

• Molecular Formula:

  C15H18N2

• Molecular Weight:

  226.32

• References & Citations:

  [1]Bruhwyler J, et al. Pirlindole: a selective reversible inhibitor of monoamine oxidase A. A review of its preclinical properties. Pharmacol Res. 1997 Jul;36 (1) :23-33. |[2]Ulferts R, et al. Screening of a Library of FDA-Approved Drugs Identifies Several Enterovirus Replication Inhibitors That Target Viral Protein 2C. Antimicrob Agents Chemother. 2016 Apr 22;60 (5) :2627-38.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, sealed storage, away from moisture)

• Scientific Category:

  Reference compound1

• Clinical Information:

  Launched

• CAS Number:

  [60762-57-4]