Benzophenone

• Description :

  Benzophenone is an endogenous metabolite. Benzophenone is a photosensitizer, that absorbs UV light, transfers its energy to DNA, and triggers DNA damage. Benzophenone can be used as the fragrance enhancer, ultraviolet curing agent, additive in plastics, or the flavor ingredient. Benzophenone can also be used in the manufacturing of insecticides, agricultural chemicals, hypnotics, antihistamines, and other pharmaceuticals. Benzophenone exhibits certain carcinogenicity in mouse/rat models under long term exposure. Benzophenone exhibits estrogenic activity[1][2].

• UNSPSC :

  12352005

• Hazard Statement :

  H350, H373, H401, H412

• Target :

  Endogenous Metabolite; Photosensitizer

• Type :

  Natural Products

• Related Pathways :

  Apoptosis; Metabolic Enzyme/Protease

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/benzophenone.html

• Concentration :

  10mM

• Purity :

  99.99

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  O=C(C1=CC=CC=C1)C2=CC=CC=C2

• Molecular Formula :

  C13H10O

• Molecular Weight :

  182.22

• Precautions :

  H350, H373, H401, H412

• References & Citations :

  [1]EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF) ; Silano V, et al., Safety of benzophenone to be used as flavouring. EFSA J. 2017 Nov 14;15 (11) :e05013.|[2]Rhodes MC, et al., Carcinogenesis studies of benzophenone in rats and mice. Food Chem Toxicol. 2007 May;45 (5) :843-51.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [119-61-9]