Products for Research Use Only
RegisterLogin

RecombinantEpigen, Human

CAT: 0013-GTR18991824-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR18991824-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Epigen is a cytokine belonging to the Epidermal Growth Factor (EGF) superfamily, which also includes Epiregulin, Amphiregulin, Neuregulin 2-β, and Transforming Growth Factor α. The precursor of Epigen produced in tissues has 154 amino acids, and shares the characteristics of other members of EGF superfamily, including 3 disulfide bonds formed by 6 cysteines. Epigen is present in testis, heart, and liver, and it binds to EGF receptors with a much lower binding affinity than EGF. However, Epigen is more mitogenic than EGF. Epigen achieves its strong mitogenic potency by suppressing ligand-induced receptor inactivation. Unlike EGF, Epigen can also bind to EGF receptors in low pH conditions, helping its recycling. Therefore Epigen has anomalous potency due to its prolonged presence.Recombinant human Epigen (rhEpigen) produced in E.coli is a single non-glycosylated polypeptide chain containing 73 amino acids. A fully biologically active molecule, rhEpigen has a molecular mass of 8.1 kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript.
Product Name Alternative
EPG, Epithelial mitogen
Source
Escherichia coli.
Endotoxin
< 0.2 EU/μg, determined by LAL method.
Purity
> 95% by SDS-PAGE analysis.
Bioactivity
ED50 1x 10ˆ3 units/mg.
Form
Lyophilized after extensive dialysis against PBS.
Molecular Weight
8.1 kDa, observed by reducing SDS-PAGE.
Storage Conditions
Lyophilized recombinant human Epigen (rhEpigen) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rhEpigen remains stable up to 2 weeks at 4°C or up to 3 months at -20°C.
Notes
For research use only.
Applications Notes
Reconstituted in ddH2O at 100 μg/mL.
Preservative
Lyophilized after extensive dialysis against PBS.
AA Sequence
MAVTVTPPI TAQQADNIEG PIALKFSHLC LEDHNSYCIN GACAFHHELE KAICRCFTGY TGERCEHLTL TSYA

Related Products

CatalogName
GTR18777889-01Human Human CYP19A1 Antibody
GTR18882498-01Human human Septin-7 protein
GTR18880605-01Human Human Septin-7 protein
GTR18834069-01Human Human Macrosialin ELISA Kit
GTR19008890-01Human BDNF (BDNF Human) protein
GTR18698434-01HuMax-IL8 Human Monoclonal Antibody
GTR18698323-01HuMax-IL15 Human Monoclonal Antibody
GTR17702017Rabbit Human Sirt1 Protein (Human) Antibody
GTR18877893Human Human IgG3 Lambda G3M (G)
GTR18895534-01Human HspH1

Alternative Products

CatalogName
BK0031-01RecombinantEpigen, Human
BK0031RecombinantEpigen,Human
BK0197-01RecombinantEpigen, Human (CHO-expressed)
BK0197RecombinantEpigen,Human(CHO-expressed)
P83251PMG36e-ADH1B (human-opt-human) -ALDH2 (human-opt-human)
P81559PCMV-Twinstrep-UFM1 (human) -UFM1 (human-opt-human) -UFM1 (human-opt-human) -Neo
9230-10Human CellExp™ Human CD40/ TNFRSF5, Human recombinant
P1493-200Human CellExp™ Human Serum Albumin, Human Recombinant
PT_75080-01Adiponectin Human (Acrp30 Human)
PT_42362-01Urokinase Human (Urokinase Human)

Popular Products