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Raptinal

CAT: 0804-HY-121320-02Size: 10 mM - 1 mLDry Ice: NoHazardous: No
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CAT#:0804-HY-121320-02Size:10 mM - 1 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Raptinal, a agent that directly activates caspase-3, initiates intrinsic pathway caspase-dependent apoptosis. Raptinal is able to rapidly induce cancer cell death by directly activating the effector caspase-3, bypassing the activation of initiator caspase-8 and caspase-9[1][2].
CAS Number
1176-09-6
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Apoptosis; Caspase
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/raptinal.html
Purity
98.0
Solubility
DMSO : 20 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=CC1(C2(C=O)C3=C(C4=C2C=CC=C4)C=CC=C3)C5=C(C6=C1C=CC=C6)C=CC=C5
Molecular Formula
C28H18O2
Molecular Weight
386.44
Precautions
H315, H319, H335
References & Citations
H. pyloriBIRC3
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Caspase 3

Chemical Information

9H,9'H-(9,9'-bifluorene)-9,9'-dicarbaldehyde
CAS Number1176-09-6
PubChem CID355994
IUPAC Name9-(9-formylfluoren-9-yl)fluorene-9-carbaldehyde
Molecular FormulaC28H18O2
Molecular Weight386.4
XLogP4.9
Topological Polar Surface Area34.1
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count3
Heavy Atom Count30
Formal Charge0
Complexity580
SMILES
C1=CC=C2C(=C1)C3=CC=CC=C3C2(C=O)C4(C5=CC=CC=C5C6=CC=CC=C64)C=O
InChI
InChI=1S/C28H18O2/c29-17-27(23-13-5-1-9-19(23)20-10-2-6-14-24(20)27)28(18-30)25-15-7-3-11-21(25)22-12-4-8-16-26(22)28/h1-18H
InChIKey
GLANOOJJBKXTMI-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 9H,9'H-(9,9'-bifluorene)-9,9'-dicarbaldehyde
CAS: 1176-09-6
CID: 355994
Formula: C28H18O2
MW: 386.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight386.4
XLogP34.9
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count3
Exact Mass386.130679813
Monoisotopic Mass386.130679813
Topological Polar Surface Area34.1 Ų
Heavy Atom Count30
Formal Charge0
Complexity580
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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