Acid-PEG3-C2-Boc

• UNSPSC Description:

  Acid-PEG3-C2-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs for the degradation of EGFR and inhibition of mTOR[1][2].

• Target Antigen:

  PROTAC Linkers

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/acid-peg3-c2-boc.html

• Purity:

  97.0

• Solubility:

  10 mM in DMSO

• Smiles:

  CC(C)(C)OC(CCOCCOCCOCCC(O)=O)=O

• Molecular Weight:

  306.35

• References & Citations:

  [1]Nathanael Gray, et al. Bifunctional molecules for degradation of egfr and methods of use. WO2017185036A1.|[2]Christopher Semko, et al. Rapamycin analogs as mtor inhibitors. WO 2018204416 A1.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  1807539-06-5