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AZ5385

CAT: 0804-HY-163377Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-163377Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AZ5385 is an EGFR-tyrosine kinase inhibitor. AZ5385 is a HRV-2 virus blocker, with EC50 of 0.35 µM. AZ5385 affects the late stage of viral life cycle[1].
CAS Number
848439-89-4
UNSPSC
12352005
Target
EGFR; Enterovirus
Type
Reference compound
Related Pathways
Anti-infection; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/az5385.html
Solubility
10 mM in DMSO
Smiles
C[C@H](O)C(N(CC1)CCC1OC(C(O)=C2)=CC3=C2C(NC4=C(C(Cl)=CC=C4)F)=NC=N3)=O
Molecular Formula
C22H22ClFN4O4
Molecular Weight
460.89
References & Citations
[1]Miah M, et al. Identification of epidermal growth factor receptor-tyrosine kinase inhibitor targeting the VP1 pocket of human rhinovirus. Antimicrob Agents Chemother. 2024 Mar 6;68 (3) :e0106423.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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