Products for Research Use Only
RegisterLogin

Obacunone

CAT: 0804-HY-N0428-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-N0428-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Obacunone is a highly oxidized triterpenoid limonoid isolated from citrus plants. Obacunone exerts its anticancer effects by inducing apoptosis. Obacunone also protects retinal pigment epithelial (RPE) cells from ultraviolet (UV) radiation (UVR) -induced oxidative damage[1][2][3].
CAS Number
751-03-1
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis
Type
Natural Products
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/obacunone.html
Concentration
10mM
Purity
99.75
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(OC1(C)C)C=C[C@]([C@@]1([H])C2)(C)[C@@]3([H])CC[C@]4(C)[C@@]([C@H]5C(O[C@H]4C6=COC=C6)=O)(O5)[C@]3(C)C2=O
Molecular Formula
C26H30O7
Molecular Weight
454.51
Precautions
H302, H315, H319, H335
References & Citations
[1]Chidambara Murthy KN, et al. Obacunone and obacunone glucoside inhibit human colon cancer (SW480) cells by the induction of apoptosis. Food Chem Toxicol. 2011 Jul;49 (7) :1616-25.|[2]Huang DR, et al. Obacunone protects retinal pigment epithelium cells from ultra-violet radiation-induced oxidative injury. Aging (Albany NY) . 2021 Feb 1;13 (8) :11010-11025.|[3]Xu S, et al. Obacunone activates the Nrf2-dependent antioxidant responses. Protein Cell. 2016 Sep;7 (9) :684-8.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

Alternative Products

CatalogName
MBS3609067-01Obacunone
371750Obacunone discontinued
S3784-01Obacunone (AI3-37934)

Popular Products