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TH470

CAT: 0804-HY-151539-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-151539-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TH470 is a highly selective LIMK1/2 (LIM kinase1/2) inhibitor (LIMK1 IC50=9.8 nM; LIMK2 IC50=13 nM), and can be used in orphan disease research[1].
CAS Number
2834739-51-2
UNSPSC
12352005
Target
LIM Kinase (LIMK)
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/th470.html
Purity
99.57
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(C(NC1=NC=C(S1)C(NCCN(C(C2=CC=C(C=C2)S(=O)(NC3=CC=CC=C3)=O)=O)CC4=CC=CC=C4)=O)=O)C
Molecular Formula
C30H31N5O5S2
Molecular Weight
605.73
References & Citations
[1]Hanke T, et al. Development and Characterization of Type I, Type II, and Type III LIM-Kinase Chemical Probes. J Med Chem. 2022 Oct 13;65 (19) :13264-13287.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
LIMK1; LIMK2

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CatalogName
BA4228-5TH470

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