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ME0328

CAT: 0804-HY-100225-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-100225-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ME0328 is a potent and selective ARTD3/PARP3 inhibitor with an IC50 of 0.89±0.28 μM.
CAS Number
1445251-22-8
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PARP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ME0328.html
Purity
99.64
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(N[C@H](C1=CC=CC=C1)C)CCC(NC2=C3C=CC=C2)=NC3=O
Molecular Formula
C19H19N3O2
Molecular Weight
321.37
Precautions
H302, H315, H319, H335
References & Citations
[1]Lindgren AE, et al. PARP inhibitor with selectivity toward ADP-ribosyltransferase ARTD3/PARP3. ACS Chem Biol. 2013 Aug 16;8 (8) :1698-703.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PARP1; PARP10; PARP2; PARP3; TNKS1/PARP5A; TNKS2/PARP5B

Alternative Products

CatalogName
27634-2ME0328
A14309-25ME0328 25mg
A14309-5ME0328 5mg
A14309-100ME0328 100mg
A14309-10ME0328 10mg
A14309-50ME0328 50mg
A14309-10mM-DME0328 10mM * 1mL in DMSO

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