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EV206

CAT: 0804-HY-168566Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-168566Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EV206 is a potent Hsp70 inhibitor. EV206 shows antiproliferative activity. EV206 induces apoptosis and increases the protein expression of cleaved PARP and caspase-3. EV206 shows antitumor activity[1].
CAS Number
2247047-81-8
UNSPSC
12352005
Target
HSP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ev206.html
Smiles
O=C1C2=C(C=CC=C2)N(CC=C)C(N1CC3)C4=C3C5=CC=CC=C5N4
Molecular Formula
C21H19N3O
Molecular Weight
329.40
References & Citations
[1]Min HY, et al. Development of a novel N14-substituted antitumor evodiamine derivative with inhibiting heat shock protein 70 in non-small cell lung cancer. Sci Rep. 2024 Oct 25;14 (1) :25436.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HSP70

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CatalogName
GTR19239916-01EV206

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