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NOTCH1 Antibody Blocking peptide

CAT: 0013-GTR18964804Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18964804Size:500 µg
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Description
NOTCH1 Antibody Blocking peptide
Product Name Alternative
Neurogenic locus notch homolog protein 1, Notch 1, hN1, Translocation-associated notch protein TAN-1, Notch 1 extracellular truncation, NEXT, Notch 1 intracellular domain, NICD, NOTCH1, TAN1
UniProt
P46531
Field of Research
Cardiovascular Research
Form
Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Notes
For research use only.
Applications Notes
Synthetic peptide
AA Sequence
The synthetic peptide sequence was selected from the C-term region of human NOTCH1 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

UniProtKB · P46531

Neurogenic locus notch homolog protein 1

NOTC1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P46531
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
NOTCH1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
Notch 1, hN1
EC number
—
Processing
Precursor
Secondary accessions
Q59ED8, Q5SXM3
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Molecular function

ActivatorDevelopmental proteinReceptor

Biological process

AngiogenesisDifferentiationNotch signaling pathwayTranscriptionTranscription regulation

Domain

ANK repeatEGF-like domainRepeatSignalTransmembraneTransmembrane helix

Ligand

CalciumMetal-binding

Cellular component

Cell membraneEndosomeMembraneNucleus

Disease

Disease variant

PTM

Disulfide bondGlycoproteinHydroxylationIsopeptide bondPhosphoproteinUbl conjugation

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